You can set up an automatic response to any mail message coming to your email address. Auto-reply is a standard means to notify your correspondents that you are out of the office or on vacation.
How To Create Or Manage An Email Auto-Reply
Log in to the Client Area
Click on Products
Under Categories select Web Hosting
Click View Details next to the account you wish to manage
Click Manage / Login To Plesk
Click on Mail (left hand side menu) and select the email address you wish to manage. Then click on the Auto-Reply tab
Tick the box to enable (or disable) the Auto-reply
You can now adjust the subject and text that will be sent to people when they email you. Typically we would recommend plain text and UTF-8 encoding for maximum compatibility, though mostly everyone supports HTML formatted emails now. You can also add an attachment and redirect a copy of any emails received onto another address, if someone is monitoring the address in your absence. Just don't forget to disable the auto-reply when you get back by unticking the box again.